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Acceptance Test Cases

At the very heart of the Infermedica platform lies a vast, constantly growing database of clinical cases. We validate them with complete rigor to ensure our engine’s accuracy. As transparency is one of our core values, we present a list of sample test cases and their results.

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Current pass rate

Sample test cases

95.98%

Last test

June 1, 2021

Last test

June 1, 2021

Testing process

Infermedica’s diagnostic engine is tested by carrying out assessments on thousands of well documented clinical cases. How does it work? We send requests to our API and receive the results, which you can see on the selected test cases list below. The accuracy is confirmed when the diagnostic engine ranks the condition within the top 3 or top 5 positions—depending on the complexity of the case—of the differential diagnosis ranking.

Testing process illustration

Selected test cases

A representative sample of clinical cases, selected from thousands that we regularly test our diagnostics engine on:

ICD-10

Condition

Age

Test result

K05

Gingivitis

26 years

Test passed badge

Passed

26-year-old female with gingivitis

ICD-10: K05

Present symptoms:

Symptom present mark

Bleeding gums Initial

Symptom present mark

Halitosis Initial

Symptom present mark

Swollen gums Initial

Symptom present mark

Deepening of periodontal pockets

Symptom present mark

Dental plaque

Symptom present mark

Gum erythema

Symptom present mark

Gum pain

Absent symptoms:

None

Source:

Aggressive periodontitis with streptococcal gingivitis: a case report. Eur J Dent. 2007;1(4):251-255.

Test passed badge

Test passed

Expected condition:

Gingivitis in top 3

Predicted conditions:

Gingivitis Prediction successful mark

Periodontitis

H90.3 , H90.4

Sudden sensorineural hearing loss

53 years

Test passed badge

Passed

53-year-old female with sudden sensorineural hearing loss

ICD-10: H90.3, H90.4

Present symptoms:

Symptom present mark

Decreased hearing Initial

Symptom present mark

Decreased hearing, sudden hearing loss Initial

Symptom present mark

Tinnitus Initial

Absent symptoms:

None

Source:

Sudden sensorineural hearing loss and delayed complete sudden spontaneous recovery. J Am Acad Audiol. 2012;23(4):249-255. https://doi.org/10.3766/jaaa.23.4.3

Test passed badge

Test passed

Expected condition:

Sudden sensorineural hearing loss in top 3

Predicted conditions:

Sudden sensorineural hearing loss Prediction successful mark

Earwax blockage

Acute otitis media

Vertebrobasilar insufficiency

Cerebellopontine angle syndrome

N60.1

Fibrocystic breasts

42 years

Test passed badge

Passed

42-year-old lady with a tender lump in her right breast

ICD-10: N60.1

Present symptoms:

Symptom present mark

Breast pain or tenderness, unilateral Initial

Symptom present mark

Nodule located in breast Initial

Symptom present mark

Breast pain or tenderness, bilateral

Symptom present mark

Dermatological changes

Symptom present mark

Hormonal contraceptive or menopausal hormone therapy

Symptom present mark

Skin mass

Symptom present mark

Skin mass greater than 1 cm in diameter

Absent symptoms:

Symptom absent mark

Chronic heavy alcohol use

Symptom absent mark

Smoking cigarettes

Source:

Oxford Cases in Medicine and Surgery. Farne H, Norris-Cervetto E, Warbrick-Smith J. Oxford University Press; 2010, page 222

Test passed badge

Test passed

Expected condition:

Fibrocystic breasts in top 3

Predicted conditions:

Non-lactational mastitis

Fibrocystic breasts Prediction successful mark

Breast cancer

Fibroadenoma of breast

N80.0

Adenomyosis

45 years

Test passed badge

Passed

45-year-old female with intermittent low back pain

ICD-10: N80.0

Present symptoms:

Symptom present mark

Abdominal pain, pelvic Initial

Symptom present mark

Back pain, lumbar Initial

Symptom present mark

Back pain, severe Initial

Symptom present mark

Dysmenorrhea Initial

Symptom present mark

Heavy or prolonged menstrual periods Initial

Symptom present mark

Abdominal pain, left lower quadrant

Symptom present mark

Abdominal pain, right lower quadrant

Symptom present mark

Depressed mood

Symptom present mark

Fatigue

Absent symptoms:

Symptom absent mark

Vaginal bleeding, negative or unknown pregnancy status

Source:

Intermittent low back pain referred from a uterine adenomyosis: a case report. J Chiropr Med. 2011;10(1):64-69. https://dx.doi.org/10.1016%2Fj.jcm.2010.08.004

Test passed badge

Test passed

Expected condition:

Adenomyosis in top 5

Predicted conditions:

Adenomyosis Prediction successful mark

Endometriosis

Sciatica

Uterine fibroids

Degenerative disc disease of the lumbar and sacral spine

Mechanical back pain

Spinal osteoarthritis

B35.3

Tinea pedis

37 years

Test passed badge

Passed

37-year-old female with left foot pain

ICD-10: B35.3

Present symptoms:

Symptom present mark

Dermatological changes Initial

Symptom present mark

Dermatological changes, feet Initial

Symptom present mark

Pain in one foot Initial

Symptom present mark

Thickened nails Initial

Symptom present mark

Dermatological changes, painful

Symptom present mark

Edema

Symptom present mark

Erythema

Symptom present mark

Pruritus

Symptom present mark

Pruritus, foot

Symptom present mark

Skin desquamation

Symptom present mark

Skin thickening

Symptom present mark

Thickened nails with pits or grooves

Symptom present mark

Yellow nail discoloration

Absent symptoms:

None

Source:

Top 50 Dermatology Case Studies for Primary Care. Reich D, Psomadakis CE, Buka B. Springer; 2016, case 15

Test passed badge

Test passed

Expected condition:

Tinea pedis in top 3

Predicted conditions:

Tinea pedis Prediction successful mark

Onychomycosis

Psoriasis

M31.1

Thrombotic thrombocytopenic purpura

49 years

Test failed badge

Failed

49-yea-old female with arm and leg weakness

ICD-10: M31.1

Present symptoms:

Symptom present mark

Fatigue Initial

Symptom present mark

Muscle weakness Initial

Symptom present mark

Consciousness disturbances

Symptom present mark

Fever

Symptom present mark

High cholesterol

Symptom present mark

Hypertension

Symptom present mark

Hypertension, over 140 mmHg

Symptom present mark

Petechiae

Absent symptoms:

Symptom absent mark

Chronic heavy alcohol use

Symptom absent mark

Impaired vision

Symptom absent mark

Smoking cigarettes

Source:

100 Cases In Acute Medicine. Kerry Lane, Henry Fok, Adam Nabeebaccus. 2012. Case 30, page 59-60.

Test failed badge

Test failed

Expected condition:

Thrombotic thrombocytopenic purpura in top 3

Predicted conditions:

Sepsis

COVID-19

Hypertension

Bacterial meningitis

Cushing's syndrome

Polyarteritis nodosa

Hashimoto's thyroiditis

D59.3

Hemolytic-uremic syndrome

25 years

Test failed badge

Failed

25-year-old male with abdominal pain, vomiting and bloody diarrhoea

ICD-10: D59.3

Present symptoms:

Symptom present mark

Abdominal pain Initial

Symptom present mark

Blood in stool Initial

Symptom present mark

Diarrhea Initial

Symptom present mark

Vomiting Initial

Symptom present mark

Abdominal pain, lasting less than two days

Symptom present mark

Hypotension

Symptom present mark

Pale skin

Symptom present mark

Tachycardia

Absent symptoms:

None

Source:

100 Cases In Acute Medicine. Kerry Lane, Henry Fok, Adam Nabeebaccus. 2012. Case 18, page 35-36.

Test failed badge

Test failed

Expected condition:

Hemolytic-uremic syndrome in top 3

Predicted conditions:

Bacterial gastroenteritis

Viral gastroenteritis

Cardiac tamponade

Intestinal obstruction

Food poisoning

Dehydration

Acute upper gastrointestinal bleeding

F50.0 , F50.1

Anorexia

17 years

Test passed badge

Passed

17-year-old female with drowsiness and lethargy

ICD-10: F50.0, F50.1

Present symptoms:

Symptom present mark

Amenorrhea, secondary

Symptom present mark

Bradycardia

Symptom present mark

Dizziness

Symptom present mark

Fatigue

Symptom present mark

Feeling overweight despite low weight

Symptom present mark

Hypotension

Symptom present mark

Reduced body temperature

Symptom present mark

Weight faltering

Absent symptoms:

None

Source:

100 Cases In Acute Medicine. Kerry Lane, Henry Fok, Adam Nabeebaccus. 2012. Case 59, page 133-134

Test passed badge

Test passed

Expected condition:

Anorexia in top 3

Predicted conditions:

Anorexia Prediction successful mark

K92.2

Acute upper gastrointestinal bleeding

45 years

Test passed badge

Passed

45-year old male with coffee-ground vomiting

ICD-10: K92.2

Present symptoms:

Symptom present mark

Abdominal pain, epigastric Initial

Symptom present mark

Hematemesis Initial

Symptom present mark

Nausea Initial

Symptom present mark

Abdominal pain

Symptom present mark

Abdominal pain, burning or gnawing

Symptom present mark

Abdominal pain, lasting more than two weeks

Symptom present mark

Abdominal tenderness

Symptom present mark

Black stools

Symptom present mark

Vomiting

Absent symptoms:

Symptom absent mark

Abdominal mass

Symptom absent mark

Chronic NSAIDs use

Symptom absent mark

Hepatomegaly

Symptom absent mark

Splenomegaly

Source:

100 Cases In Clinical Pathology. Eamon Shamil, Praful Ravi, Ashish Chandra. 2014. Case 44, page 125-127.

Test passed badge

Test passed

Expected condition:

Acute upper gastrointestinal bleeding in top 3

Predicted conditions:

Gastritis

Acute upper gastrointestinal bleeding Prediction successful mark

Zollinger-Ellison syndrome

Peptic ulcer

Functional dyspepsia

L50

Chronic urticaria

26 years

Test passed badge

Passed

26-year-old female with itchy eruption

ICD-10: L50

Present symptoms:

Symptom present mark

Pruritus Initial

Symptom present mark

Urticaria Initial

Symptom present mark

Annular skin lesions

Symptom present mark

Dermatological changes

Symptom present mark

Dermatological changes, located on the face

Symptom present mark

Dermatological changes, recurring during infections or menstrual period

Symptom present mark

Dermatological changes, with flare-ups and remissions

Symptom present mark

Enlarged cervical lymph nodes

Symptom present mark

Erythema

Symptom present mark

Rash

Symptom present mark

Tachycardia

Symptom present mark

Tremors

Symptom present mark

Urticaria triggered by heat

Symptom present mark

Urticaria, lasting more than six weeks

Absent symptoms:

Symptom absent mark

Abdominal tenderness

Symptom absent mark

Urticaria triggered by cold

Symptom absent mark

Urticaria triggered by prolonged pressure on the skin

Source:

100 Cases in Dermatology. Morris-Jones R, Powell AM, Benton E. CRC Press; 2011, page 19-22

Test passed badge

Test passed

Expected condition:

Chronic urticaria in top 3

Predicted conditions:

Chronic urticaria Prediction successful mark

Common cold

Systemic lupus erythematosus

Oral herpes

J20 , J20.9 , ...

Acute bronchitis

58 years

Test passed badge

Passed

58-year-old woman with productive cough

ICD-10: J20, J20.9, J68.0

Present symptoms:

Symptom present mark

Cough, paroxysmal Initial

Symptom present mark

Cough, productive Initial

Symptom present mark

Pharyngeal erythema Initial

Symptom present mark

Cough

Symptom present mark

Cough, lasting less than three weeks

Symptom present mark

Cough, productive with yellow or green sputum

Symptom present mark

Fatigue

Symptom present mark

Fever between 98 and 100.4°F (37 and 38°C)

Symptom present mark

Pharyngeal pain

Symptom present mark

Sleep disorder

Absent symptoms:

Symptom absent mark

Chest pain

Symptom absent mark

Hemoptysis

Symptom absent mark

Jaw pain

Symptom absent mark

Nasal catarrh

Symptom absent mark

Postnasal drip

Symptom absent mark

Vomiting

Source:

Essential Family Medicine. Fundamentals and Case Studies. Rakel RE. Saunders; 2006, page 287

Test passed badge

Test passed

Expected condition:

Acute bronchitis in top 3

Predicted conditions:

Acute bronchitis Prediction successful mark

COVID-19

Acute viral tonsillopharyngitis

Pneumonia

Acute laryngitis

Acute streptococcal tonsillopharyngitis

Common cold

I21 , I22

Myocardial infarction

56 years

Test passed badge

Passed

56-years-old male with myocardial infarction

ICD-10: I21, I22

Present symptoms:

Symptom present mark

Chest pain, sudden Initial

Symptom present mark

Anxiety

Symptom present mark

Chest pain, continues after rest

Symptom present mark

Chest pain, diffuse

Symptom present mark

Chest pain, lasting between 30 minutes and 8 hours

Symptom present mark

Chest pain, radiating to left upper limb

Symptom present mark

Chest pain, substernal

Symptom present mark

Dyspnea

Symptom present mark

Dyspnea, lasting less than 1 hour

Symptom present mark

Hypertension

Symptom present mark

Recent travel to Asia excluding Middle East, Russia, Mongolia and Kazakhstan

Symptom present mark

Recent travel to Europe

Symptom present mark

Tachypnea

Absent symptoms:

Symptom absent mark

Chest pain, radiating between shoulder blades

Symptom absent mark

Chest pain, severe

Symptom absent mark

Chest pain, stabbing

Symptom absent mark

Contact with allergen

Symptom absent mark

Diagnosed diabetes

Symptom absent mark

Dyspnea, lasting 1 day to 4 weeks

Symptom absent mark

Dyspnea, lasting more than 4 weeks

Symptom absent mark

Excessive sweating

Symptom absent mark

Fever

Symptom absent mark

High cholesterol

Symptom absent mark

Recent surgery

Symptom absent mark

Smoking cigarettes

Source:

External validation study

Test passed badge

Test passed

Expected condition:

Myocardial infarction in top 3

Predicted conditions:

Myocardial infarction Prediction successful mark

Unstable angina pectoris

A38

Scarlet fever

29 years

Test passed badge

Passed

29-year-old French man living in Tokyo with a fever, sore throat and rash

ICD-10: A38

Present symptoms:

Symptom present mark

Fever Initial

Symptom present mark

Pharyngeal pain Initial

Symptom present mark

Rash Initial

Symptom present mark

Scarlet fever rash

Symptom present mark

Skin desquamation

Symptom present mark

Strawberry tongue

Symptom present mark

Tongue erythema

Absent symptoms:

None

Source:

Scarlet fever in an adult. Intern Med. 2014;53(2):167-168. https://doi.org/10.2169/internalmedicine.53.1486

Test passed badge

Test passed

Expected condition:

Scarlet fever in top 3

Predicted conditions:

Scarlet fever Prediction successful mark

G56.0

Carpal tunnel syndrome

43 years

Test passed badge

Passed

43-year-old woman with painful burning and tingling in both her hands

ICD-10: G56.0

Present symptoms:

Symptom present mark

Pain in fingers or hand Initial

Symptom present mark

Muscle weakness

Symptom present mark

Paresthesia

Symptom present mark

Paresthesia in both upper limbs, glove distribution

Symptom present mark

Tingling fingers

Absent symptoms:

None

Source:

General Surgery: Correlations and Clinical Scenarios for the USMLE Step 3. Sonpal N, Fisher C. McGraw-Hill Education; 2015, Case 1

Test passed badge

Test passed

Expected condition:

Carpal tunnel syndrome in top 3

Predicted conditions:

Carpal tunnel syndrome Prediction successful mark

Mixed connective tissue disease

Guillain-Barré syndrome

Systemic scleroderma

Raynaud's phenomenon

Cervical radiculopathy

L05 , L05.0 , ...

Pilonidal cyst

9 years

Test passed badge

Passed

A 9-year-old female with pilonidal cyst

ICD-10: L05, L05.0, L05.9

Present symptoms:

Symptom present mark

Dermatological changes, painful Initial

Symptom present mark

Skin mass, natal cleft Initial

Symptom present mark

Buttocks pain

Symptom present mark

Erythema

Absent symptoms:

None

Source:

Acceptance test cases created in according to IN-02-01-01 Standard acceptance test case (saTC) guideline

Test passed badge

Test passed

Expected condition:

Pilonidal cyst in top 3

Predicted conditions:

Pilonidal cyst Prediction successful mark

Warts

Miliaria

Contact dermatitis

Seborrheic dermatitis

Acne

Atopic dermatitis

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Data illustration
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