Acceptance Test Cases

At the very heart of the Infermedica platform lies a vast, constantly growing database of clinical cases. We validate them with complete rigor to ensure our engine’s accuracy. As transparency is one of our core values, we present a list of sample test cases and their results.

Current pass rate

Sample test cases

95.98%

Last test

June 1, 2021

Last test

June 1, 2021

Testing process

Infermedica’s diagnostic engine is tested by carrying out assessments on thousands of well documented clinical cases. How does it work? We send requests to our API and receive the results, which you can see on the selected test cases list below. The accuracy is confirmed when the diagnostic engine ranks the condition within the top 3 or top 5 positions—depending on the complexity of the case—of the differential diagnosis ranking.

Selected test cases

A representative sample of clinical cases, selected from thousands that we regularly test our diagnostics engine on:

Show:

ICD-10

Condition

Age

Test result

K05

Gingivitis

26 years

Passed

26-year-old female with gingivitis

ICD-10: K05

Present symptoms:

Bleeding gums Initial

Halitosis Initial

Swollen gums Initial

Deepening of periodontal pockets

Dental plaque

Gum erythema

Gum pain

Absent symptoms:

None

Source:

Aggressive periodontitis with streptococcal gingivitis: a case report. Eur J Dent. 2007;1(4):251-255.

Test passed

Expected condition:

Gingivitis in top 3

Predicted conditions:

Gingivitis Prediction successful mark

Periodontitis

H90.3 , H90.4

Sudden sensorineural hearing loss

53 years

Passed

53-year-old female with sudden sensorineural hearing loss

ICD-10: H90.3, H90.4

Present symptoms:

Decreased hearing Initial

Decreased hearing, sudden hearing loss Initial

Tinnitus Initial

Absent symptoms:

None

Source:

Sudden sensorineural hearing loss and delayed complete sudden spontaneous recovery. J Am Acad Audiol. 2012;23(4):249-255. https://doi.org/10.3766/jaaa.23.4.3

Test passed

Expected condition:

Sudden sensorineural hearing loss in top 3

Predicted conditions:

Sudden sensorineural hearing loss Prediction successful mark

Earwax blockage

Acute otitis media

Vertebrobasilar insufficiency

Cerebellopontine angle syndrome

N60.1

Fibrocystic breasts

42 years

Passed

42-year-old lady with a tender lump in her right breast

ICD-10: N60.1

Present symptoms:

Breast pain or tenderness, unilateral Initial

Nodule located in breast Initial

Breast pain or tenderness, bilateral

Dermatological changes

Hormonal contraceptive or menopausal hormone therapy

Skin mass

Skin mass greater than 1 cm in diameter

Absent symptoms:

Chronic heavy alcohol use

Smoking cigarettes

Source:

Oxford Cases in Medicine and Surgery. Farne H, Norris-Cervetto E, Warbrick-Smith J. Oxford University Press; 2010, page 222

Test passed

Expected condition:

Fibrocystic breasts in top 3

Predicted conditions:

Non-lactational mastitis

Fibrocystic breasts Prediction successful mark

Breast cancer

Fibroadenoma of breast

N80.0

Adenomyosis

45 years

Passed

45-year-old female with intermittent low back pain

ICD-10: N80.0

Present symptoms:

Abdominal pain, pelvic Initial

Back pain, lumbar Initial

Back pain, severe Initial

Dysmenorrhea Initial

Heavy or prolonged menstrual periods Initial

Abdominal pain, left lower quadrant

Abdominal pain, right lower quadrant

Depressed mood

Fatigue

Absent symptoms:

Vaginal bleeding, negative or unknown pregnancy status

Source:

Intermittent low back pain referred from a uterine adenomyosis: a case report. J Chiropr Med. 2011;10(1):64-69. https://dx.doi.org/10.1016%2Fj.jcm.2010.08.004

Test passed

Expected condition:

Adenomyosis in top 5

Predicted conditions:

Adenomyosis Prediction successful mark

Endometriosis

Sciatica

Uterine fibroids

Degenerative disc disease of the lumbar and sacral spine

Mechanical back pain

Spinal osteoarthritis

B35.3

Tinea pedis

37 years

Passed

37-year-old female with left foot pain

ICD-10: B35.3

Present symptoms:

Dermatological changes Initial

Dermatological changes, feet Initial

Pain in one foot Initial

Thickened nails Initial

Dermatological changes, painful

Edema

Erythema

Pruritus

Pruritus, foot

Skin desquamation

Skin thickening

Thickened nails with pits or grooves

Yellow nail discoloration

Absent symptoms:

None

Source:

Top 50 Dermatology Case Studies for Primary Care. Reich D, Psomadakis CE, Buka B. Springer; 2016, case 15

Test passed

Expected condition:

Tinea pedis in top 3

Predicted conditions:

Tinea pedis Prediction successful mark

Onychomycosis

Psoriasis

M31.1

Thrombotic thrombocytopenic purpura

49 years

Failed

49-yea-old female with arm and leg weakness

ICD-10: M31.1

Present symptoms:

Fatigue Initial

Muscle weakness Initial

Consciousness disturbances

Fever

High cholesterol

Hypertension

Hypertension, over 140 mmHg

Petechiae

Absent symptoms:

Chronic heavy alcohol use

Impaired vision

Smoking cigarettes

Source:

100 Cases In Acute Medicine. Kerry Lane, Henry Fok, Adam Nabeebaccus. 2012. Case 30, page 59-60.

Test failed

Expected condition:

Thrombotic thrombocytopenic purpura in top 3

Predicted conditions:

Sepsis

COVID-19

Hypertension

Bacterial meningitis

Cushing's syndrome

Polyarteritis nodosa

Hashimoto's thyroiditis

D59.3

Hemolytic-uremic syndrome

25 years

Failed

25-year-old male with abdominal pain, vomiting and bloody diarrhoea

ICD-10: D59.3

Present symptoms:

Abdominal pain Initial

Blood in stool Initial

Diarrhea Initial

Vomiting Initial

Abdominal pain, lasting less than two days

Hypotension

Pale skin

Tachycardia

Absent symptoms:

None

Source:

100 Cases In Acute Medicine. Kerry Lane, Henry Fok, Adam Nabeebaccus. 2012. Case 18, page 35-36.

Test failed

Expected condition:

Hemolytic-uremic syndrome in top 3

Predicted conditions:

Bacterial gastroenteritis

Viral gastroenteritis

Cardiac tamponade

Intestinal obstruction

Food poisoning

Dehydration

Acute upper gastrointestinal bleeding

F50.0 , F50.1

Anorexia

17 years

Passed

17-year-old female with drowsiness and lethargy

ICD-10: F50.0, F50.1

Present symptoms:

Amenorrhea, secondary

Bradycardia

Dizziness

Fatigue

Feeling overweight despite low weight

Hypotension

Reduced body temperature

Weight faltering

Absent symptoms:

None

Source:

100 Cases In Acute Medicine. Kerry Lane, Henry Fok, Adam Nabeebaccus. 2012. Case 59, page 133-134

Test passed

Expected condition:

Anorexia in top 3

Predicted conditions:

Anorexia Prediction successful mark

K92.2

Acute upper gastrointestinal bleeding

45 years

Passed

45-year old male with coffee-ground vomiting

ICD-10: K92.2

Present symptoms:

Abdominal pain, epigastric Initial

Hematemesis Initial

Nausea Initial

Abdominal pain

Abdominal pain, burning or gnawing

Abdominal pain, lasting more than two weeks

Abdominal tenderness

Black stools

Vomiting

Absent symptoms:

Abdominal mass

Chronic NSAIDs use

Hepatomegaly

Splenomegaly

Source:

100 Cases In Clinical Pathology. Eamon Shamil, Praful Ravi, Ashish Chandra. 2014. Case 44, page 125-127.

Test passed

Expected condition:

Acute upper gastrointestinal bleeding in top 3

Predicted conditions:

Gastritis

Acute upper gastrointestinal bleeding Prediction successful mark

Zollinger-Ellison syndrome

Peptic ulcer

Functional dyspepsia

L50

Chronic urticaria

26 years

Passed

26-year-old female with itchy eruption

ICD-10: L50

Present symptoms:

Pruritus Initial

Urticaria Initial

Annular skin lesions

Dermatological changes

Dermatological changes, located on the face

Dermatological changes, recurring during infections or menstrual period

Dermatological changes, with flare-ups and remissions

Enlarged cervical lymph nodes

Erythema

Rash

Tachycardia

Tremors

Urticaria triggered by heat

Urticaria, lasting more than six weeks

Absent symptoms:

Abdominal tenderness

Urticaria triggered by cold

Urticaria triggered by prolonged pressure on the skin

Source:

100 Cases in Dermatology. Morris-Jones R, Powell AM, Benton E. CRC Press; 2011, page 19-22

Test passed

Expected condition:

Chronic urticaria in top 3

Predicted conditions:

Chronic urticaria Prediction successful mark

Common cold

Systemic lupus erythematosus

Oral herpes

J20 , J20.9 , ...

Acute bronchitis

58 years

Passed

58-year-old woman with productive cough

ICD-10: J20, J20.9, J68.0

Present symptoms:

Cough, paroxysmal Initial

Cough, productive Initial

Pharyngeal erythema Initial

Cough

Cough, lasting less than three weeks

Cough, productive with yellow or green sputum

Fatigue

Fever between 98 and 100.4°F (37 and 38°C)

Pharyngeal pain

Sleep disorder

Absent symptoms:

Chest pain

Hemoptysis

Jaw pain

Nasal catarrh

Postnasal drip

Vomiting

Source:

Essential Family Medicine. Fundamentals and Case Studies. Rakel RE. Saunders; 2006, page 287

Test passed

Expected condition:

Acute bronchitis in top 3

Predicted conditions:

Acute bronchitis Prediction successful mark

COVID-19

Acute viral tonsillopharyngitis

Pneumonia

Acute laryngitis

Acute streptococcal tonsillopharyngitis

Common cold

I21 , I22

Myocardial infarction

56 years

Passed

56-years-old male with myocardial infarction

ICD-10: I21, I22

Present symptoms:

Chest pain, sudden Initial

Anxiety

Chest pain, continues after rest

Chest pain, diffuse

Chest pain, lasting between 30 minutes and 8 hours

Chest pain, radiating to left upper limb

Chest pain, substernal

Dyspnea

Dyspnea, lasting less than 1 hour

Hypertension

Recent travel to Asia excluding Middle East, Russia, Mongolia and Kazakhstan

Recent travel to Europe

Tachypnea

Absent symptoms:

Chest pain, radiating between shoulder blades

Chest pain, severe

Chest pain, stabbing

Contact with allergen

Diagnosed diabetes

Dyspnea, lasting 1 day to 4 weeks

Dyspnea, lasting more than 4 weeks

Excessive sweating

Fever

High cholesterol

Recent surgery

Smoking cigarettes

Source:

External validation study

Test passed

Expected condition:

Myocardial infarction in top 3

Predicted conditions:

Myocardial infarction Prediction successful mark

Unstable angina pectoris

A38

Scarlet fever

29 years

Passed

29-year-old French man living in Tokyo with a fever, sore throat and rash

ICD-10: A38

Present symptoms:

Fever Initial

Pharyngeal pain Initial

Rash Initial

Scarlet fever rash

Skin desquamation

Strawberry tongue

Tongue erythema

Absent symptoms:

None

Source:

Scarlet fever in an adult. Intern Med. 2014;53(2):167-168. https://doi.org/10.2169/internalmedicine.53.1486

Test passed

Expected condition:

Scarlet fever in top 3

Predicted conditions:

Scarlet fever Prediction successful mark

G56.0

Carpal tunnel syndrome

43 years

Passed

43-year-old woman with painful burning and tingling in both her hands

ICD-10: G56.0

Present symptoms:

Pain in fingers or hand Initial

Muscle weakness

Paresthesia

Paresthesia in both upper limbs, glove distribution

Tingling fingers

Absent symptoms:

None

Source:

General Surgery: Correlations and Clinical Scenarios for the USMLE Step 3. Sonpal N, Fisher C. McGraw-Hill Education; 2015, Case 1

Test passed

Expected condition:

Carpal tunnel syndrome in top 3

Predicted conditions:

Carpal tunnel syndrome Prediction successful mark

Mixed connective tissue disease

Guillain-Barré syndrome

Systemic scleroderma

Raynaud's phenomenon

Cervical radiculopathy

L05 , L05.0 , ...

Pilonidal cyst

9 years

Passed

A 9-year-old female with pilonidal cyst

ICD-10: L05, L05.0, L05.9

Present symptoms:

Dermatological changes, painful Initial

Skin mass, natal cleft Initial

Buttocks pain

Erythema

Absent symptoms:

None

Source:

Acceptance test cases created in according to IN-02-01-01 Standard acceptance test case (saTC) guideline

Test passed

Expected condition:

Pilonidal cyst in top 3

Predicted conditions:

Pilonidal cyst Prediction successful mark

Warts

Miliaria

Contact dermatitis

Seborrheic dermatitis

Acne

Atopic dermatitis

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Our testing model imitates the behaviour of our API after sending a request with the symptoms from the test case. This means you can experience our engine accuracy firsthand - download the JSON file and test our engine.

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Acceptance Test Cases

Testing process

Selected test cases