Acceptance Test Cases

At the very heart of the Infermedica platform lies a vast, constantly growing database of clinical cases. We validate them with complete rigor to ensure our engine’s accuracy. As transparency is one of our core values, we present a list of sample test cases and their results.

Current pass rate

Sample test cases

97.52%

Last test

Jan 12, 2021

Last test

Jan 12, 2021

Testing process

Infermedica’s diagnostic engine is tested by carrying out assessments on thousands of well documented clinical cases. How does it work? We send requests to our API and receive the results, which you can see on the selected test cases list below. The accuracy is confirmed when the diagnostic engine ranks the condition within the top 3 or top 5 positions—depending on the complexity of the case—of the differential diagnosis ranking.

Selected test cases

A representative sample of clinical cases, selected from thousands that we regularly test our diagnostics engine on:

Show:

ICD-10

Condition

Test result

K05

Gingivitis

Passed

26-year-old female with gingivitis

ICD-10: K05

Present symptoms:

Bleeding gums Initial

Halitosis Initial

Swollen gums Initial

Deepening of periodontal pockets

Dental plaque

Gum erythema

Gum pain

Absent symptoms:

None

Source:

Kara C, Demir T, Tezel A, Zihni M. Aggressive periodontitis with streptococcal gingivitis: a case report. Eur J Dent. 2007;1(4):251-255.

Test passed

Expected condition:

Gingivitis in top 3

Predicted conditions:

Gingivitis Prediction successful mark

Periodontitis

H90.3 , H90.4

Sudden sensorineural hearing loss

Passed

53-year-old female with sudden sensorineural hearing loss

ICD-10: H90.3, H90.4

Present symptoms:

Decreased hearing Initial

Decreased hearing, sudden hearing loss Initial

Tinnitus Initial

Absent symptoms:

None

Source:

Ortmann AJ, Neely JG. Sudden sensorineural hearing loss and delayed complete sudden spontaneous recovery. J Am Acad Audiol. 2012;23(4):249-255. doi:10.3766/jaaa.23.4.3

Test passed

Expected condition:

Sudden sensorineural hearing loss in top 3

Predicted conditions:

Sudden sensorineural hearing loss Prediction successful mark

Earwax blockage

Acute otitis media

Perforation of tympanic membrane

Vertebrobasilar insufficiency

Cerebellopontine angle syndrome

N60.1

Fibrocystic breasts

Passed

42-year-old lady with a tender lump in her right breast

ICD-10: N60.1

Present symptoms:

Breast pain or tenderness, unilateral Initial

Nodule located in breast Initial

Breast pain or tenderness, bilateral

Dermatological changes

Hormonal contraceptive or menopausal hormone therapy

Skin mass

Skin mass greater than 1 cm in diameter

Absent symptoms:

Chronic heavy alcohol use

Smoking cigarettes

Source:

Farne H, Norris-Cervetto E, Warbrick-Smith J. Oxford Cases in Medicine and Surgery. Oxford University Press; 2010, page 222

Test passed

Expected condition:

Fibrocystic breasts in top 3

Predicted conditions:

Non-lactational mastitis

Fibrocystic breasts Prediction successful mark

Breast cancer

Fibroadenoma of breast

N80.0

Adenomyosis

Passed

45-year-old female with intermittent low back pain

ICD-10: N80.0

Present symptoms:

Abdominal pain, pelvic Initial

Back pain, lumbar Initial

Back pain, severe Initial

Dysmenorrhea Initial

Heavy or prolonged menstrual periods Initial

Abdominal pain, left lower quadrant

Abdominal pain, right lower quadrant

Depressed mood

Fatigue

Absent symptoms:

Vaginal bleeding, negative or unknown pregnancy status

Source:

Jensen AM, Bewketu B, Sanford D. Intermittent low back pain referred from a uterine adenomyosis: a case report. J Chiropr Med. 2011;10(1):64-69. doi:10.1016/j.jcm.2010.08.004

Test passed

Expected condition:

Adenomyosis in top 5

Predicted conditions:

Adenomyosis Prediction successful mark

Uterine fibroids

Sciatica

Degenerative disc disease of the lumbar and sacral spine

Mechanical back pain

Endometriosis

Spinal osteoarthritis

B35.3

Tinea pedis

Passed

37-year-old female with left foot pain

ICD-10: B35.3

Present symptoms:

Dermatological changes Initial

Dermatological changes, feet Initial

Pain in one foot Initial

Thickened nails Initial

Dermatological changes, painful

Edema

Erythema

Pruritus

Pruritus, foot

Skin desquamation

Skin thickening

Thickened nails with pits or grooves

Yellow nail discoloration

Absent symptoms:

None

Source:

Reich D, Psomadakis CE, Buka B. Top 50 Dermatology Case Studies for Primary Care. Springer; 2016, case 15

Test passed

Expected condition:

Tinea pedis in top 3

Predicted conditions:

Tinea pedis Prediction successful mark

Onychomycosis

G44.2

Tension-type headaches

Passed

45-year-old man with headache

ICD-10: G44.2

Present symptoms:

Headache Initial

Headache, chronic Initial

Headache, forehead

Headache, pressing

Headache, series over a period of time

Absent symptoms:

Nausea

Source:

Macleod M, Simpson M, Pal S. Neurology: Clinical Cases Uncovered. Wiley-Blackwell; 2011, case 25

Test passed

Expected condition:

Tension-type headaches in top 3

Predicted conditions:

Cluster headaches

Tension-type headaches Prediction successful mark

Chronic sinusitis

Migraine

Trigeminal neuralgia

L25

Contact dermatitis

Passed

59-year-old male with itchy patch

ICD-10: L25

Present symptoms:

Dermatological changes Initial

Dermatological changes, at the point of contact with buttons, fasteners, or cosmetics Initial

Pruritus Initial

Dermatological changes, hyperpigmentation of the skin

Dermatological changes, rough and irregular surface

Erythema

Absent symptoms:

None

Source:

Morris-Jones R, Powell AM, Benton E. 100 Cases in Dermatology. CRC Press; 2011, page 13-15

Test passed

Expected condition:

Contact dermatitis in top 3

Predicted conditions:

Contact dermatitis Prediction successful mark

Acute urticaria

Tinea pedis

L50

Chronic urticaria

Passed

26-year-old female with itchy eruption

ICD-10: L50

Present symptoms:

Pruritus Initial

Urticaria Initial

Annular skin lesions

Dermatological changes

Dermatological changes, located on the face

Dermatological changes, recurring during infections or menstrual period

Dermatological changes, with flare-ups and remissions

Erythema

Palpable neck mass

Rash

Tachycardia

Tremors

Urticaria triggered by heat

Urticaria, present for more than six weeks

Absent symptoms:

Abdominal tenderness

Urticaria triggered by cold

Urticaria triggered by prolonged pressure on the skin

Source:

Morris-Jones R, Powell AM, Benton E. 100 Cases in Dermatology. CRC Press; 2011, page 19-22

Test passed

Expected condition:

Chronic urticaria in top 3

Predicted conditions:

Chronic urticaria Prediction successful mark

Contact dermatitis

Oral herpes

N40

Benign prostatic hyperplasia

Passed

63-year-old male with difficulty voiding

ICD-10: N40

Present symptoms:

Bladder not emptying completely Initial

Frequent urination Initial

Trouble beginning urination Initial

Hypertension

Absent symptoms:

Abdominal mass

Discharge from urethra

Fever

Pain while urinating

Source:

Toy EC, Ross LM, Papasakelariou C, Zhang H. Case Files Anatomy 3rd Edition. McGraw-Hill Education; 2014, case 31, page 209

Test passed

Expected condition:

Benign prostatic hyperplasia in top 3

Predicted conditions:

Benign prostatic hyperplasia Prediction successful mark

J20 , J20.9 , ...

Acute bronchitis

Passed

58-year-old woman with productive cough

ICD-10: J20, J20.9, J68.0

Present symptoms:

Cough, paroxysmal Initial

Cough, productive Initial

Pharyngeal erythema Initial

Cough

Cough, lasting less than three weeks

Cough, productive with yellow or green sputum

Fatigue

Fever between 98 and 100.4°F (37 and 38°C)

Pharyngeal pain

Sleep disorder

Absent symptoms:

Chest pain

Hemoptysis

Jaw pain

Nasal catarrh

Postnasal drip

Vomiting

Source:

Rakel RE. Essential Family Medicine. Fundamentals and Case Studies. Saunders; 2006, page 287

Test passed

Expected condition:

Acute bronchitis in top 3

Predicted conditions:

Acute bronchitis Prediction successful mark

Acute viral tonsillopharyngitis

Pneumonia

Acute streptococcal tonsillopharyngitis

J09 , J10 , ...

Influenza

Passed

45-year-old female with abrupt onset of sore throat, nonproductive cough, chills, and mild fever

ICD-10: J09, J10, J11

Present symptoms:

Chills Initial

Cough, dry Initial

Fever Initial

Pharyngeal pain Initial

Cough

Diminished appetite

Dizziness

Dyspnea

Fatigue

Fever between 100.4 and 104°F (38 and 40°C)

Headache

Joint pain

Myalgia

Nausea

Tachypnea

Absent symptoms:

None

Source:

Gilligan PH, Shapiro DS, Miller MB. Cases in Medical Microbiology and Infectious Diseases. ASM Press; 2014, case 10

Test passed

Expected condition:

Influenza in top 3

Predicted conditions:

Pneumonia

Influenza Prediction successful mark

I21 , I22

Myocardial infarction

Passed

56-years-old male with myocardial infarction

ICD-10: I21, I22

Present symptoms:

Chest pain, sudden Initial

Anxiety

Chest pain, continues after rest

Chest pain, diffuse

Chest pain, lasting between 30 minutes and 8 hours

Chest pain, radiating to left upper limb

Chest pain, substernal

Dyspnea

Dyspnea, lasting less than 1 hour

Hypertension

Recent travel to Asia excluding Middle East, Russia, Mongolia and Kazakhstan

Recent travel to Europe

Tachypnea

Absent symptoms:

Chest pain, radiating between shoulder blades

Chest pain, severe

Chest pain, stabbing

Contact with allergen

Diagnosed diabetes

Dyspnea, lasting 1 day to 4 weeks

Dyspnea, lasting more than 4 weeks

Excessive sweating

Fever

High cholesterol

Recent surgery

Smoking cigarettes

Source:

External validation study

Test passed

Expected condition:

Myocardial infarction in top 3

Predicted conditions:

Myocardial infarction Prediction successful mark

Unstable angina pectoris

A38

Scarlet fever

Passed

29-year-old French man living in Tokyo with a fever, sore throat and rash

ICD-10: A38

Present symptoms:

Fever Initial

Pharyngeal pain Initial

Rash Initial

Scarlet fever rash

Skin desquamation

Strawberry tongue

Tongue erythema

Absent symptoms:

None

Source:

Kutsuna S, Hayakawa K, Ohmagari N. Scarlet fever in an adult. Intern Med. 2014;53(2):167-168. doi:10.2169/internalmedicine.53.1486

Test passed

Expected condition:

Scarlet fever in top 3

Predicted conditions:

Scarlet fever Prediction successful mark

G56.0

Carpal tunnel syndrome

Passed

43-year-old woman with painful burning and tingling in both her hands

ICD-10: G56.0

Present symptoms:

Pain in fingers or hand Initial

Paresthesia, limbs Initial

Muscle weakness

Paresthesia

Paresthesia in both upper limbs, glove distribution

Symptoms worsen in evening

Tingling fingers

Absent symptoms:

None

Source:

Sonpal N, Fisher C. General Surgery: Correlations and Clinical Scenarios for the USMLE Step 3. McGraw-Hill Education; 2015, Case 1

Test passed

Expected condition:

Carpal tunnel syndrome in top 3

Predicted conditions:

Carpal tunnel syndrome Prediction successful mark

Guillain-Barré syndrome

Mixed connective tissue disease

J45 , J45.0 , ...

Asthma

Passed

32-year-old man with occasional wheezing

ICD-10: J45, J45.0, J45.1, J45.8, J45.9

Present symptoms:

Wheezing, audible Initial

Chest pain

Contact with allergen

Dyspnea

Dyspnea, on exertion

Dyspnea, paroxysmal nocturnal

Dyspnea, with flare-ups and remissions

Absent symptoms:

Fever

Smoking cigarettes

Source:

Stern S, Cifu A, Altkorn D. Symptom to Diagnosis: An Evidence-Based Guide, 2nd Edition, USA; 2010, page 467

Test passed

Expected condition:

Asthma in top 3

Predicted conditions:

Asthma Prediction successful mark

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Acceptance Test Cases

Testing process

Selected test cases